Background and Purpose: Spiritual intelligence and self-esteem are complementary to human’s life, which give meaning to its various aspects.
They enable people to use their experiences for finding a solution to life’s difficulties and feel satisfied. Regarding this, the aim of the present study was to predict life satisfaction based on spiritual intelligence and selfesteem.
      Materials and Methods: This descriptive and correlational study was conducted on the Master of Science students, who were newly admitted to Islamic Azad University of Roodehen, Iran, using the convenience sampling method. For data collection, the Life Satisfaction Test, Spiritual Intelligence Questionnaire, and Self-esteem Scale were employed. The data were analyzed using Pearson product-moment correlation, multiple regression analysis, and independent t-test.
      Results: According to the results of the study, the spiritual intelligence and self-esteem had a positive effect of 0.22 on life satisfaction, which is
statistically significant. According to the coefficient of determination, it was found that 22% of the variance of the students’ life satisfaction could be explained by predictor variables (i.e., spiritual intelligence and self-esteem). Furthermore, the spiritual intelligence (t=7.28) and self-esteem (t=4.54) were
found to be the statistically significant predictor variables (P=0.001).
     Conclusion: As the results of the present study demonstrated, the spiritual intelligence and self-esteem are considered as predictors of life satisfaction among students.