Background and Purpose: Anxiety is one of the most common mental health problems in the current society. The present study was carried out to investigate the levels of spiritual health and anxiety in students of Faculty of Nursing and Midwifery of Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Materials and Methods: This cross-sectional, descriptive-analytical study was performed on 314 students of Faculty of Nursing and Midwifery in Rafsanjan, Iran. Data was acquired using the Palutzian and Ellison questionnaire of spiritual well-being and Beck Anxiety Inventory. The obtained data was analyzed using parametric statistical tests such as independent t-test in SPSS 20.

Results: Spiritual health was at a moderate level (49.4%), while anxiety was low (33%) among these students. We noted a negative correlation between spiritual health and anxiety (r=-0.398).

Conclusion: As spiritual well-being diminishes anxiety, our results indicated the significance of addressing spirituality in students of Nursing and Midwifery. To promote spirituality in these students, appropriate plans should be adopted.